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Cushing's Disease Case study

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Q 1.1. Differentiate between adrenal and pituitary Cushing's. Explain why the symptoms of Cushing's are the same, despite the cause being different. 2. 2. Based on the symptoms of Cushing's, explain whether or not its actions are anabolic or catabolic. Use evidence from the case study for justification. 3. 3. The dexamethasone suppression test is used to determine if Cushing's is pituitary based. Explain why cortisol should remain elevated in those with secondary pathology.

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1.Cushing disease is a rare disorder which occurs due to overproduction of cortisol by the adrenal gland. When the tumor of the adrenal gland produces too much cortisol then it is called as adrenal Cushing . If the hormone cortisol is produced by the pituitary gland then it is called as pituitary Cushing’s. The symptoms are same due to the production of the same hormone cortisol from different sources .