In case of mannerism, there is the presence of sophistication of the intellectual elements of the human minds (Matthews, Noble & Platt, 2014). However, in case of humanism, there is the presence of more concentration on the practical, rational and human elements of the society and environment (Matthews, Noble & Platt, 2014). There is more elegance in the ways in which artwork with mannerism is portrayed. There is also more utilization of stylish elements as well as cultural elements in case of portraying artwork by supporters of mannerism (Matthews, Noble & Platt, 2014).