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– Nelson Mandela

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Hunt A Diagnosis Scenario 2

Hunt A Diagnosis Scenario 2

Q Questions: 1. What is a pedigree and what are they used for? (2 pt) 2. What is Brugada syndrome and what are the causes of Brugada syndrome? (2 pt) 3. What is the function of voltage-gated sodium channels in the heart? (2 pts) 4. Who is most at risk of Brugada syndrome? (2 pts) 5. Does Brugada syndrome only effect men? (1 pt) 6. Do you think Mr. Wang’s cause of death may have been sudden cardiac death from Brugada Syndrome? Why or why not? (4 pt)

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1. Pedigree is a genetic representation or diagram of a family tree which shows the pattern of flow of inheritance of a disease or trait through a number of generations. The pedigree is used for determining this time of flow of inheritance among a family tree through several generations of that particular family, such as from great grandparents to grandchildren. The specialty or use of this pedigree tree is that it can explain the traits of individual members separately and also express if there is any silent carrier of trait