Opioid has become life threatening and it ravages the human lives. Opioid seems to hit the minority people in the urban precinct but soon it expands its wings to the different corner of the city. It has already taken million lives in America and now the treatment to get rid of the addiction is an hour of need. According to Manchikanti, et al., Opioid is formed with the combinations of the other drugs OxyContin, Percocet, Methadone and Buprenorphine (Manchikanti, et al.).